Minako Karahashi1, Tomoko Koumura1, Kiyoshi Kawasaki2, Masahiro Nishijima3, Yasuhito Nakagawa1 (1 Sch. of Pharmaceutical Sci., Kitasato Univ., 2 Sch. of Pharmaceutical Sci., Doshisha Women's College, 3 Natl. Inst. Health Sci.)

Yuichiro Sato, Sadamitsu Asoh, Riri Kitazawa, Ikuroh Ohsawa and Shigeo Ohta (Department of Biochemistry and Cell Biology, Institute of Gerontology, Nippon Medical School.)

Hiroka Fujita, Taro Sakamoto and Yasuhito Nakagawa (Sch. of Pharmaceutical Sci., Kitasato University)

Alexander Wolf, Ikuroh Ohsawa, Shigeo Ohta (Department of Biochemistry and Cell Biology, Institute of Development and Aging Sciences, Nippon Medical School)

Eri Mikami1,2), Noriyuki Fuku2), Takashi Kawahara3), Hideyuki Takahashi3) , Nao Ohiwa3) , Yutaka Nishigaki2), Mitsuru Higuchi1), Masashi Tanaka2) (1) Waseda University, 2)Tokyo Metropolitan Institute of Gerontology, 3)Japan Institute of Sports Sciences)

Yasuhiro Kitazoe1, Hirohisa Kishino2, Masami Hasegawa3, Noriaki Nakajima1, Jeffrey L. Thorne4, Masashi Tanaka5 (1Center of Medical Information Science, Kochi Medical School, Japan. 2Graduate School of Agricultural and Life Sciences, University of Tokyo, Japan. 3School of Life Sciences, Fudan University, China., 4Bioinformatics Research Center, North Carolina State University, USA. 5Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Japan)

Yuichi Matsushima and Laurie S. Kaguni (Department of Biochemistry and Molecular Biology, and Center for Mitochondrial Science and Medicine, Michigan State University)

Hideyuki Hatakeyama, Hirofumi Komaki, and Yu-ichi Goto (Dept. 2, Natl. Inst. Neurosci., Natl. Ctr. Neuro. & Psychiatry, Japan)

Ling Feng, Minoru Yoshida, Takehiko Shibata (RIKEN Advanced Science Institute)

Kei Murayama 1), Tomoko Tsuruoka 1), Yoshitami Sanayama 1), Hironori Nagasaka 1), Masato Mori 2), Hiroko Harashima 3), Masaki Takayanagi1), Akira Ohtake3) (1) Dpt. of Metabolism, Chiba Children’s Hospital, Japan 2) Dpt. of Pediatrics, Jichi Med. Univ. Japan 3) Dpt. of Pediatrics, Saitama Med. School, Japan)

Akira Sudo1,3), Kana Hosoki3), Taro Matsuoka4), Tomoshiro Ito1,3), Hitomi Sano1), Naoki Fukushima1), Toshinao Takenouchi2), Kei Murayama5), Akira Ohtake6), Shinji Saitoh3), Yu-ichi Goto7), (1) Department of Pediatrics, Sapporo City General Hospital, 2) Department of Pathology, Sapporo City General Hospital, 3) Department of Pediatrics, Hokkaido University Graduate School of Medicine, 4) Department of Pediatrics, Toyonaka Municipal Hospital)

Yutaka Nishigaki1, Hitomi Ueno1, Hiroko Hosoya1, Noriyuki Fuku1, Michio Hirano2 and Masashi Tanaka1 (1) Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Japan, 2) Department of Neurology, Columbia University, USA)

Akira Ohtake1), Kei Murayama2), Hiroko Harashima1), Taro Yamazaki1), Masakazu Honda1), Yoshitami Sanayama2), Tomoko Tsuruoka2), Hiroyasu Iwasa3), Yasushi Okazaki3), Masaki Takayanagi2) (1)Department of Pediatrics, and 3)Division of Translational Research, Research Center for Genomic Medicine, Saitama Medical University, 2)Department of Metabolism, Chiba Children’s Hospital)

Alexandra Gtz MSc1*, Pirjo Isohanni MD 1,2* Helena Pihko MD, PhD2 , Anders Paetau MD PhD3, Riitta Herva MD PhD4 Outi Saarenp-Heikkil MD, PhD5, Leena Valanne MD PhD6, Sanna Marjavaara PhD1, Anu Suomalainen MD, PhD 1,7 (1 Research Programme of Molecular Neurology, Biomedicum-Helsinki, and 6 Helsinki Medical Imaging Center, University of Helsinki, Finland 2 Departments of Paediatric Neurology, Hospital for Children and Adolescents, and 7 Neurology, Helsinki University Central Hospital, Finland., 3 Department of Pathology, University of Helsinki and Helsinki University Central Hospital, Finland., 4 Department of Pathology, Oulu University Hospital, Finland, 5 Paediatric Clinics, Tampere University Hospital, Finland)

Eric Dufour2, Emmanuel P Dassa1, Gertjan A J Hakkart2, Kirsty Allan2, Raphael Guillot2, Pivi Turunen2, Marika Vha-Jaakkola2, Eric Shoubridge4, Howard T Jacobs2,3, Pierre Rustin1 (1Inserm, U676 and Universit Paris 7, Facult de Mdecine Denis Diderot, France, 2Institute of Medical Technology and Tampere University Hospital, University of Tampere, Finland, 3Institute of Biomedical and Life Sciences, University of Glasgow, UK and 4Department of Human Genetics McGill University, Canada)

Gyesoon Yoon, Ph.D. (Dept. of Biochemistry, Ajou University School of Medicine; Dept. of Mol. Sci. & Tech. (BK21), Graduate School, Ajou University, Korea)

Chan Bae Park, PhD (Institute for Medical sciences, Ajou University School of Medicine, S. Korea)

Masahiro Higuchi Ph.D (Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences)

Kojiro Takeda, Sakura Kikuchi, Koji Nagao, Aya Kokubu, Tomoko Yoshida, and Mitsuhiro Yanagida (Okinawa Institute for Science and Technology, Japan)

Mihoko MATSUZAKI1,2), Kazutoshi NAKANO1), Tomohiro NAKAYAMA1), Toshiyuki IWAMATSU1), Makiko OSAWA1), Kenta UTO3), Chiharu AOKI3), Kazuho HONDA3) and Hideaki ODA3) (1) Department of Pediatrics, Tokyo Women's Medical University　2) Nakagawa-no-sato Rehabilitation Center 3) Department of Pathology, Tokyo Women's Medical University)